Muktar 2018 - Untangling Cortical Complexity During Development

 

• the cerebral cortex is composed of billions of morphologically and functionally distinct neurons which need to be precisely organized during development in order for them to encode complex cognitive functions.
• Paper also discussed various methods used for characterizing neuronal subtypes such as fate mapping, genome-wide analysis and transcriptome profiling which can help us better understand cortical complexity.
• Insight into how these findings could be applied practically when studying neurological disorders or memory formation by understanding precisely how different types of neurons interact with each other during development.

Fate mapping is a method used to characterize neuronal subtypes in the cerebral cortex. It involves tracing and labeling cells of different types during development, which allows researchers to track their fate as they differentiate into distinct cell types. This technique can be used to study how neurons are produced, organized and connected during development in order for them encode complex cognitive functions such as memory formation or neurological conditions like autism.