Mosconi et al 2015

 Key Takeaways. 

• Autistics show disruptions in both feedforward and feedback motor control mechanisms, implicating anterior and posterior cerebellar circuits 
• The severity of visuomotor abnormalities in autism is dependent on the level of demand on the motor system, with increased reliance on slower feedback mechanisms observed.
• Autistics exhibit a profile of motor control abnormalities similar to those seen in patients with cerebellar lesions, suggesting intrinsic alterations in cerebellar circuits in autism.
• Disruptions in feedforward control of force output are observed in autism, even when joint-coordination functions are not required, indicating impairments in planning functions of the cerebellum.

Mosconi, M. W., Mohanty, S., Greene, R. K., Cook, E. H., Vaillancourt, D. E., & Sweeney, J. A. (2015). Feedforward and feedback motor control abnormalities implicate cerebellar dysfunctions in autism spectrum disorder. Journal of Neuroscience, 35(5)